Chulalongkorn University Dental Journal

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The effect of sodium fluoride on acid production of Streptococcus mutans BHT. in the presence of glucose has been investigated. It was found that preincubation of cells in the buffer with fluoride (1, 5, or 10 mM) for 10 minutes before adding glucose (10 mM) resulted in the reduction of the initial rate of acidification. The end pH was also increased in correspond to fluoride concentration. It was noted that the addition of fluoride at pH 6.0 did not change the initial rate of pH reduction. However, the pH at which acid production stopped was about the same values.



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