Chulalongkorn University Dental Journal

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Objective The purpose of this study was to compare between enamel fluoride uptake after professional topical fluoride gel application and self applied CPP-ACP paste with professional topical fluoride gel. Materials and methods Forty children, aged from 10 to 12 were recruited and divided into two groups. Control group was applied professional topical fluoride gel and experimental group was self applied CPP-ACP paste after professional topical fluoride gel for 4 weeks. Acid-etched enamel biopsy was performed on labial surfaces of both right and left sides on permanent upper central incisors. Enamel sample was collected before applying fluoride gel, 30 minutes and 4 weeks after fluoride gel application. The enamel biopsy sample was measured to determine fluoride concentration and calcium concentration by using fluoride electrode and atomic absorption spectrophotometer, respectively. The data was analyzed by Mann-Whitney U Test and one way repeated measures analysis of variance at significant level 0.05 Results This study found that enamel fluoride uptake after 4 week fluoride gel application between control group (2145.11 ± 193.18 parts per million) and experimental group (4172.41 ± 273.17 parts per million) was statistically significant difference (p < 0.05). The difference of enamel fluoride uptake between before applying fluoride gel and after 4 weeks, there was not statistically significant difference (p > 0.05) in control group but there was statistically significant difference (p < 0.05) in experimental group. Conclusion The findings of this investigation can be concluded that CPP-ACP paste affects on the enamel fluoride uptake after applying fluoride gel for 4 weeks.



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