Chulalongkorn University Dental Journal

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Objective To compare the prevalence and species of Candida in the oral cavity of denture wearers and non-denture wearers. Materials and methods A total of 80 subjects were studied: 40 denture wearers and 40 non-denture wearers, matched by age and sex, comprised the experimental and control groups, respectively. Each subject was instructed to perform oral rinsing using a phosphate-buffered saline solution, which was expectorated and processed for the recovery of Candida on Sabouraudûs dextrose agar. Isolates were speciated by culturing on chromogenic candida agar and noting species-specific colony characteristics. Results The prevalence of Candida carriage was 85.00% in denture wearers and 77.50% in non-denture wearers. C. albicans was the most frequently isolated species, followed by C. tropicalis, C. glabrata, C. parapsilosis and C. krusei. The distribution of Candida species among each patient varied from one to four species. The differences in prevalence and distribution of Candida species in asymptomatic denture wearers compared to non-denture wearers were not statistically significant (p > 0.05). Conclusion Asymptomatic denture wearers and non-denture wearers did not differ in Candida carriage.



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