Chulalongkorn University Dental Journal

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The epithelial-myoepithelial carcinoma of intercalated duct origin is a rare, low-grade salivary gland neoplasm that exhibits a dual composition of both the epithelial and myoepithelial cells. This tumor can manifest a spectrum of cytomorphologic and structural features, but it classically shows duct-like structures consisting of inner cuboidal, eosinophilic, epithelial cells surrounded by clear myoepithelial cells. This review article describes the clinical features, the histopathology, the immunohistochemis- try, the treatment of this tumor and the in-depth discussion on the differential diagnosis.



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