Chulalongkorn University Dental Journal

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Objective The aim of this study was to analyse the characteristics and the management of the patients affected oral pemphigus.Material and methods The data of eight patients with oral pemphigus were collected at the Oral Medicine Department, Faculty of Dentistry, Chulalongkorn University during 1989-1997. The disease was observed mainly in women. The age range of this group was from 27-46 years, with a mean of 39.6 years. Diagnosis was based on the clinical presentation, confirmed by histopathology and immunofluorescence study. The patients were treated with prednisolone in various dosages combined with a topical steroid, 0.1% fluocinolone acetonide in solution (FAS).Results The gingiva was the most common site of the lesion in all cases. A potent topical steroid 0.1% FAS in combination with prednisolone has been found to be useful in the treatment of oral pemphigus in our findings.Conclusions The dentists are the first to detect and make the early diagnosis of oral pemphigus. Doctor and dentist cooperation play the important role to control this rare autoimmune disease.



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