Chulalongkorn Medical Journal


Background : Hyperbilirubinemia is a common problem in the neonatal period.The gold standard for the diagnosis of hyperbilirubinemia is notonly time consuming but also a painful intervention to the infant.Objective : To determine the accuracy of trancutaneous biliribinometer and todetermine an hour-specific nomogram.Material and Method : Transcutaneous bilirubin was performed on 195 healthy termneonates of gestational age greater than 37 weeks and birthweight greater than 2,500 grams using a transcutaneousbilirubinometer (Minolta, JM-103). The values of bilirubin obtainedby 2 different methods were compared: transcutaneousbilirubinometer and direct spectrophotometry, at NaresuanUniversity Hospital. We recorded transcutaneous bilirubin atthe age of 8 to 96 hours in an hour-specific nomogram.Design : Cross section prospective descriptive studySetting : Naresuan University Hospital, Phitsanulok.Result : One hundred and ninety-five neonates were recruited into thisstudy; 117 values of simultaneous transcutaneous bilirubin andmicrobilirubin were recorded. The mean transcutaneous bilirubin(TCB) was 9.5 ± 2.4 mg/dL and the mean serum microbilirubin(MB) was 10.5 ± 2.5 mg/dL. The correlation coefficient was 0.784.The hour-specific nomogram was performed at the relative risk ofthe 40th, 75th and 95th percentiles.Conclusion : The transcutaneous biliribinometer has been shown to be usefulfor the screening of hyperbilirubinemia in neonates. An hourspecifictranscutaneous bilirubin nomogram is helpful to predicthyperbilirubinemia.


Faculty of Medicine, Chulalongkorn University

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