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Chulalongkorn Medical Journal

Abstract

Background : Hyperbilirubinemia is a common problem in the neonatal period.The gold standard for the diagnosis of hyperbilirubinemia is notonly time consuming but also a painful intervention to the infant.Objective : To determine the accuracy of trancutaneous biliribinometer and todetermine an hour-specific nomogram.Material and Method : Transcutaneous bilirubin was performed on 195 healthy termneonates of gestational age greater than 37 weeks and birthweight greater than 2,500 grams using a transcutaneousbilirubinometer (Minolta, JM-103). The values of bilirubin obtainedby 2 different methods were compared: transcutaneousbilirubinometer and direct spectrophotometry, at NaresuanUniversity Hospital. We recorded transcutaneous bilirubin atthe age of 8 to 96 hours in an hour-specific nomogram.Design : Cross section prospective descriptive studySetting : Naresuan University Hospital, Phitsanulok.Result : One hundred and ninety-five neonates were recruited into thisstudy; 117 values of simultaneous transcutaneous bilirubin andmicrobilirubin were recorded. The mean transcutaneous bilirubin(TCB) was 9.5 ± 2.4 mg/dL and the mean serum microbilirubin(MB) was 10.5 ± 2.5 mg/dL. The correlation coefficient was 0.784.The hour-specific nomogram was performed at the relative risk ofthe 40th, 75th and 95th percentiles.Conclusion : The transcutaneous biliribinometer has been shown to be usefulfor the screening of hyperbilirubinemia in neonates. An hourspecifictranscutaneous bilirubin nomogram is helpful to predicthyperbilirubinemia.

Publisher

Faculty of Medicine, Chulalongkorn University

First Page

265

Last Page

273

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