Abstract
Background : Diabetes mellitus (DM) is a global epidemic and its prevalenceincreases in many region of the world. Gymnema inodorum is amedicinal plant that has been used as drug and food for a longtime in Thailand. It has hypoglycemic effect in healthy subjectswithout serious side effects. However, today there has not beenany clinical study evaluating its effect in type 2 diabetic patients.Objective : To evaluate the effect of consumption of G. inodorum tea onclinical outcomes in type 2 diabetic patients.Design : Before and after quasi-experimental study.Setting : Diabetes Clinic, Outpatient Department, Lerdsin Hospital,Bangkok.Materials and Methods : Type 2 diabetic patients voluntarily participated in the studywhich comprised of 2 consecutive phases. In the controlledphase, the patients received only prescribed drugs (week0 – week 8) and later in the treatment phase, G. inodorum teawas supplemented (week 8 – week 16). The biochemicalparameters, and nutrients and caloric intakes were evaluated atweek 0, 8, and 16.Results : The biochemical parameters including fasting blood sugar (FBS),hemoglobin A1C (HbA1C), total cholesterol (Total-C), low-densitylipoprotein cholesterol (LDL-C), high-density lipoproteincholesterol (HDL-C), triglyceride (TG), aspartate aminotransferase(AST), alanine aminotransferase (ALT), and serum creatinine(SCr) did not significantly change throughout the study. So didthe nutrient and caloric intakes.Conclusion : G. inodorum tea had no effect on blood sugar and lipid profilesin this study. It also did not affect hepatic and renal functions.
Publisher
Faculty of Medicine, Chulalongkorn University
First Page
587
Last Page
599
Recommended Citation
Bespinyowong, R; Pongthananikorn, S; and Chiabchalard, A.
(2013)
"Efficacy and safety of Gymnema inodorum tea consumptionin type 2 diabetic patients,"
Chulalongkorn Medical Journal: Vol. 57:
Iss.
5, Article 3.
Available at:
https://digital.car.chula.ac.th/clmjournal/vol57/iss5/3