Wolbachia is a group of obligatory intracellular gram-negative bacteria. This bacteriumis responsible for manipulation of host reproduction in many arthropod species and involved inembryonic and larval development, adult female fertility, and survival in filarial nematode. Theapplied biology of Wolbachia and modification of pest and vector species using Wolbachiahave been studied in order to suppress or modify natural populations. In addition, Wolbachiahas been used as a novel chemotherapeutic target for filariasis control program. This articlereviews the biology of Wolbachia in arthropods and filarial nematodes, including recent advanceand future directions of using Wolbachia as a target for vector populations control and filariasisdrug target.
Faculty of Medicine, Chulalongkorn University
Sungpradit, S and Nuchprayoon, S.
"Wolbachia of arthropods and filarial nematodes:biology and applications,"
Chulalongkorn Medical Journal: Vol. 54:
6, Article 7.
Available at: https://digital.car.chula.ac.th/clmjournal/vol54/iss6/7